Lasers and Light Source guided Osteogenesis and Angiogenesis for Tissue Engineering

Project code
PGR-P-1258
Type of research degree
PhD
Application date
Friday 31 March 2023
Project start date
Monday 3 October 2022
Country eligibility
International (open to all nationalities, including the UK)
Funding
Non-funded
Supervisors
Professor Tony Bailey and Professor Logan Fox
Additional supervisors
Dr Isla Ellis

Overview

The project will investigate the growth of osteoblast and endothelial cells in in vitro model on a given bone scaffold and investigate the light-induced cell induction and conduction for osteogenesis and angiogenesis.

The award is available to candidates who are wholly or partially self-funding and offers 10% reduction on either full academic fees or 10% reduction on the portion of academic fees that the candidate is paying if successful in securing an academic offer for a pre-defined project or their own research project. Self-funding does include parents/family who are funding on the candidate's behalf.

The biophysical aspect of the interaction of lasers in the cell culture and corresponding metabolic changes were characterized. The impact of laser power and induced changes (toxicity, cell damage, cell proliferation) will be analyzed. The research, if time permits, maybe continued by using the human stem cells for light-induced cell differentiation for angiogenesis and osteogenesis. Industry support and training may be offered as well.

Full description

The project will offer the opportunity to work closely with a team of Engineering, Orthopaedic/Trauma Surgeon, and Stem Cell Biologist for exploring a new area of research for bone tissue engineering. You will learn:

  1. Bone Scaffold engineering
  2. Biophotonic interaction of Cells for induction and conduction (Osteoblast and Endothelial cells)
  3. Apply the techniques developed in step b for osteoblast and endothelial cell growth in a tissue scaffold for future trials in animals.

How to apply

Formal applications for research degree study should be made online through the University's website. Please state clearly in the Planned Course of Study section that you are applying for PHD Chemical & Process Engineering FT in the research information section that the research degree you wish to be considered for is Lasers and Light Source guided Osteogenesis and Angiogenesis for Tissue Engineering as well as Professor Animesh Jha as your proposed supervisor.

If English is not your first language, you must provide evidence that you meet the University's minimum English language requirements (below).

Entry requirements

Applicants to research degree programmes should normally have at least a first class or an upper second class British Bachelors Honours degree (or equivalent) in an appropriate discipline. The criteria for entry for some research degrees may be higher, for example, several faculties, also require a Masters degree. Applicants are advised to check with the relevant School prior to making an application. Applicants who are uncertain about the requirements for a particular research degree are advised to contact the School or Graduate School prior to making an application.

English language requirements

The minimum English language entry requirement for research postgraduate research study is an IELTS of 6.0 overall with at least 5.5 in each component (reading, writing, listening and speaking) or equivalent. The test must be dated within two years of the start date of the course in order to be valid. Some schools and faculties have a higher requirement.

Funding on offer

Self-Funded or externally sponsored students are welcome to apply.

UK - Alumni Bursary is available to graduates of the University of Leeds.

Non-UK - The Leeds Marshall Scholarship is available to support US citizens. Alumni Bursary is available to graduates of the University of Leeds.

Please refer to the UKCISA website for information regarding Fee Status for Non-UK Nationals starting from September/October 2021.

Linked research areas

Biomaterials and tissue engineering
Cell and Organismal Biology
Molecular and Nanoscale Physics